Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
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Output Type
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Program
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CRN Team Name
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Theme
Linear diffusion modeling of tau pathology spread
Code to reproduce all network analyses in Lubben et al. “LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread”.
Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology Code: Goralsth/Spatial-transcriptomicSpatial transcriptomics Code: Spatial-transcriptomics-reveals-molecular-dysfunction-associated-with-cortical-Lewy-pathology
Code repository for Goralski, et., al., 2024.
Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology Software: DaniellaDeWeerd/ObjectAndRegionSum: ObjectAndRegionSum
This shiny app takes the output from the QUINT workflow and outputs to CSV files. One contains the object counts for certain relevant regions, and the other contains region sums for those same regions.
sPAtial Neuronal Gene Expression Atlas (PANGEA) Application
PANGEA is a web app for visualizing brain regional gene expression data. It's a spatial atlas showing gene patterns related to neurons vulnerable to α-synuclein pathology.
ASAP CRN Cloud Release Notes – Version 4.0.0
ASAP CRN Cloud released version 4.0.0 with expanded datasets including Human Postmortem-derived Brain Sequencing and Mouse datasets. New harmonized collections and individual datasets were added, enhancing research possibilities.
