Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
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Output Type
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Program
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CRN Team Name
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Theme
western blot data of ‘A new selection strategy to enrich dopaminergic neurons facilitates comparisons between patient iPSC-derived lines’
western blot data of 'A new selection strategy to enrich dopaminergic neurons facilitates comparisons between patient iPSC-derived lines'
Global Parkinson’s Genetics Program Data Release 7
In December 2025, GP2 announced the 11th data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 20,842 additional genotyped participants, 17,153 additional WGS participants, and 4,232…
Global Parkinson’s Genetics Program Data Release 8
In September 2024, GP2 announced the eighth data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 5,481 additional whole genome sequences and 10,454 clinical exome sequences. Additional…
Global Parkinson’s Genetics Program Data Release 9
In December 2024, GP2 announced the 9th data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 17,690 additional genotyped participants. The genotype array data, including…
Global Parkinson’s Genetics Program Data Release 10
In July 2025, GP2 announced the 10th data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 11,109 additional genotyped participants and 13,339 additional WGS participants. The genotype…
Global Parkinson’s Genetics Program Data Release 11
In December 2025, GP2 announced the 11th data release on the Terra and the Verily® Workbench platforms in collaboration with AMP® PD. This release includes 20,842 additional genotyped participants, 17,153 additional WGS participants, and 4,232…
Dataset for Article “Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum” by Brill-Weil et al
Dopaminergic neuron axons have GABAARs and nAChRs that influence DA release. GABAAR antagonism enhances nAChR activity, while picrotoxin inhibits nAChRs, revealing GABAARs' role in regulating nicotinic input onto DA axons.
Primary Tabular Data for article “CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology” by Liao et al
Mitochondrial dysfunction is linked to CHCHD2 mutation, causing altered protein interactions, glycolysis, and ROS, plus α-synuclein aggregation, and neurodegeneration. CHCHD2 accumulation leads to mitochondrial impairment and PD progression.
Processed Proteomics Data for Article “CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology” by Liao et al
Mitochondrial dysfunction is linked to CHCHD2 mutation, causing disrupted protein interactions, metabolic shift to glycolysis, ROS elevation, and α-synuclein aggregation. CHCHD2 accumulation leads to neurodegeneration via impaired respiration.
Human Spatial Transcriptomics data for article “CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology” by Liao et al
Mitochondrial dysfunction in Parkinson's disease involves CHCHD2 mutation leading to disrupted protein interactions, mitochondrial damage, glycolysis shift, increased ROS, and α-synuclein aggregation, linking to neurodegeneration.
Tansey Stool Meso Scale Discovery
Stool samples of healthy controls and individuals with either PD or IBD analyzed for chemokines, cytokines, and ferritin levels using U-PLEX and R-PLEX assays on Quickplex MSD instrument.
Bolen Human Sigmoid Colon Protein CosMx Datasets
Protein dataset from NanoString CosMx includes sigmoid colon samples from healthy controls, Parkinson's disease, and inflammatory bowel disease patients for analysis.
Tansey Plasma Meso Scale Discovery
Plasma samples from individuals with Parkinson's disease, inflammatory bowel disease, or healthy controls were analyzed to measure chemokines and cytokines. The study used Quickplex MSD instrument following manufacturer's protocol.
Bolen Human Sigmoid Colon RNA CosMx Dataset
NanoString CosMx RNA dataset from human sigmoid colon of healthy controls, Parkinson's Disease, or inflammatory bowel disease exported for analysis.
Generation of knock-in Cre and FlpO mouse lines for basal ganglia and dopamine neuron investigation (SOURCE DATA)
The dataset contained in this repository are the processed data and information used in all the quantifications, tables, and figures associated with the project by Albarran et al 2025 elife.
