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Output Catalog

ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.

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Tansey Stool Meso Scale Discovery

Stool samples of healthy controls and individuals with either PD or IBD analyzed for chemokines, cytokines, and ferritin levels using U-PLEX and R-PLEX assays on Quickplex MSD instrument.

Program: Collaborative Research Network
Team:
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Tansey Plasma Meso Scale Discovery

Plasma samples from individuals with Parkinson's disease, inflammatory bowel disease, or healthy controls were analyzed to measure chemokines and cytokines. The study used Quickplex MSD instrument following manufacturer's protocol.

Program: Collaborative Research Network
Team:
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Bolen Human Sigmoid Colon Protein CosMx Datasets

Protein dataset from NanoString CosMx includes sigmoid colon samples from healthy controls, Parkinson's disease, and inflammatory bowel disease patients for analysis.

Program: Collaborative Research Network
Team:
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Bolen Human Sigmoid Colon RNA CosMx Dataset

NanoString CosMx RNA dataset from human sigmoid colon of healthy controls, Parkinson's Disease, or inflammatory bowel disease exported for analysis.

Program: Collaborative Research Network
Team:
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Characterizing dysbiosis of the Parkinson’s disease gut microbiome using shotgun metagenomics

Parkinson's disease is a progressive neurodegenerative condition with altered gut microbiome composition. A study analyzed fecal samples from 490 PD patients and 234 healthy individuals to understand dysbiosis at a detailed level.

Program: Collaborative Research Network
Team:
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CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I

Protein fibril classification for Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III

Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII

Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X

Protein fibril classification for Homo sapiens, expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I

Protein fibril classification in Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II

Protein fibril from Homo sapiens expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG with no mutations reported.

Program: Collaborative Research Network
Team:
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CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III

Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V

Protein fibril classification for Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII

Protein fibril classification in Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG system without mutations.

Program: Collaborative Research Network
Team:
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CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII

Protein fibril from Homo sapiens expressed in Escherichia coli BL21-Gold(DE3)pLysS AG without mutations.

Program: Collaborative Research Network
Team:
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Aligning Science Across Parkinson's
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