Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
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Output Type
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Program
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CRN Team Name
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Theme
Tansey Stool Meso Scale Discovery
Stool samples of healthy controls and individuals with either PD or IBD analyzed for chemokines, cytokines, and ferritin levels using U-PLEX and R-PLEX assays on Quickplex MSD instrument.
Tansey Plasma Meso Scale Discovery
Plasma samples from individuals with Parkinson's disease, inflammatory bowel disease, or healthy controls were analyzed to measure chemokines and cytokines. The study used Quickplex MSD instrument following manufacturer's protocol.
Bolen Human Sigmoid Colon Protein CosMx Datasets
Protein dataset from NanoString CosMx includes sigmoid colon samples from healthy controls, Parkinson's disease, and inflammatory bowel disease patients for analysis.
Bolen Human Sigmoid Colon RNA CosMx Dataset
NanoString CosMx RNA dataset from human sigmoid colon of healthy controls, Parkinson's Disease, or inflammatory bowel disease exported for analysis.
Characterizing dysbiosis of the Parkinson’s disease gut microbiome using shotgun metagenomics
Parkinson's disease is a progressive neurodegenerative condition with altered gut microbiome composition. A study analyzed fecal samples from 490 PD patients and 234 healthy individuals to understand dysbiosis at a detailed level.
CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I
Protein fibril classification for Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III
Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X
Protein fibril classification for Homo sapiens, expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I
Protein fibril classification in Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II
Protein fibril from Homo sapiens expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG with no mutations reported.
CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III
Protein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V
Protein fibril classification for Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII
Protein fibril classification in Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG system without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII
Protein fibril from Homo sapiens expressed in Escherichia coli BL21-Gold(DE3)pLysS AG without mutations.