Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
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Output Type
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Program
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CRN Team Name
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Theme
Quantification of Axonal Projections from Whole-Brain Slide Images
Quantification of Axonal Projections from Whole-Brain Slide Images provides a standardized method for processing and analyzing immunofluorescence images of mouse brain sections to quantify axonal projections.
Genotyping protocol for mice
This protocol describes the general method to genotype the mice.
Open Field Test Parisiadou Lab
The open field test was developed to test locomotor activity.
Rotarod Test _ Parisiadou Protocol
Motor learning was assessed with an accelerating rotarod.
Dendritic Spine Analysis
Dendritic Spine Analysis for Chen et al. 2025
Striatal sections immunofluorescence and analysis
Striatal sections immunofluorescence and analysis related to LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Multicolor fluorescence in situ hybridization and analysis
Multicolor fluorescence in situ hybridization and analysis related to LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Drugs and treatment dosing
Drugs and treatment dosing protocol related to LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Acute Slice Preparation
ex vivo striatal slices
LC-MS/MS Analysis
LC-MS/MS Analysis related to LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Immunofluorescence and confocal imaging in brain sections and image analysis
Immunofluorescence and confocal imaging in brain sections and image analysis for Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons
Axonal proteome analysis and Western Blot via APEX2 labeling
Axonal proteome analysis and western blot via APEX2 labeling related to Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons
Liquid Chromatography-Mass Spectrometry (LCMS) with striatal synaptosomes
Liquid Chromatography-Mass Spectrometry (LC-MS) with striatal synaptosomes assay related to Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons preprint
SIM imaging and analysis for active zone release sites in vulnerable dopamine axons
Stereotactic injections and viruses described and SIM imaging and analysis
Western blot and Phostag gels
Western blot and Phostag gels protocol related to Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons
