Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
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Free floating immunofluorescence protocol on mouse brain sections for tau pathology
This protocol describes the process of immunofluorescently labelling tau and phospho-tau in athymic mouse brains that have been grafted with human-disease derived iPSC's. This protocol can be adapted for other tissue types and antibody pairings.
Preparation of human iPSC-derived cortical neuronal progenitors for transplantation into the rodent brain
This protocol describes how we prepare human iPSC-derived cells, that have been differentiated into cortical neuronal progenitors, for transplantation into the brain of immunocompromised athymic mice. Neuronal progenitors mature within the mouse…
