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Output Catalog

ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.

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Calf intestine alkaline phosphatase (CIAP) treatment

Protocol selectively dephosphorylates non-aggregated PSER129, improving detection of aggregated PSER129, aiding in distinguishing between physiological and disease-related forms of alpha-synuclein.

Program: Collaborative Research Network
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Purification of Proteins from PFA Fixed Samples

Protocol for purifying proteins from PFA-fixed samples and extracting proteins from formalin-fixed tissues, including biotin pulldown before LC-MS/MS. Samples used for mass spectrometry, immunoblotting, and pulldowns.

Program: Collaborative Research Network
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Multiplex Labeling with Tyramide Fluorophores (Free-Floating Tissues)-Killinger Lab 2024

Protocol for multiplex labeling of free-floating tissues with tyramide fluorophores in the Killinger lab (2024).

Program: Collaborative Research Network
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Rotarod

Rotarod protocol optimized for mice. This test is made to assess motor coordination and balance. The results should show lower latency to fall numbers for mice with motor impairments.

Program: Collaborative Research Network
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Aligning Science Across Parkinson's
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