This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Output Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
results for ""
Sort
Filter & Sort
-
Output Type
-
Program
-
CRN Team Name
-
Theme
Neuromelanin and selective neuronal vulnerability to Parkinson’s disease
Neuromelanine (NM), a pigment in human catecholamine neurons, plays a crucial role in PD. We review the development of NM in dopamine versus noradrenaline neurons and focus on previously overlooked cellular organelles in NM format and function.
Tissue Isolation of the Region Around Locus Coeruleus for Single Nucleus RNA Profiling
Isolating tissue from the peri-locus coeruleus region in mice for single nucleus RNA
Stereotaxic virus injection in the SNpc of rats
Protocol for stereotaxic virus injection in the substantia nigra pars compacta of rats
Optimized Stereotactic Injection Protocol for Targeting the Locus Coeruleus with Minimal Neurotoxicity
Refined stereotactic injection protocol targeting the Locus Coeruleus minimizes neurotoxicity.
Preparation of tissue punches of SNpc for the analyses of mitochondrial function
Protocol for the preparation of tissue punches of SNpc for the analyses of mitochondrial function
Preparation of midbrain slices for electrophysiology
Protocol for the preparation of midbrain slices for electrophysiology
Analyses of mitochondrial function in SNpc with the Seahorse XFe96
Protocol for analyses of mitochondrial function in SNpc with the Seahorse XFe96
Marble burying test
Protocol for marble burying test performed by rats
Patch-clamp recordings of SNpc dopamine neurons from midbrain slices
Protocol for patch-clamp recordings of SNpc dopamine neurons from midbrain slices
Social avoidance test
Protocol for social avoidance test performed by rats
Sucrose self-administration protocol
Protocol to evaluate sucrose self-administration in rats
Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
Reelin levels might modulate the numbers of striatal interneurons and the density of the nigrostriatal dopaminergic projections, suggesting that these changes may be involved in the protection of Reelin against neuropsychiatric disorders.
Rat brain processing for histological analyses
Protocol for rat brain processing for histological analyses.
Stereotaxic rat brain surgery for Substantia Nigra targeting
Protocol for stereotaxic rat brain surgery for Substantia Nigra targeting.
Cylinder behavioral test
Protocol for cylinder behavioral test for rats.