GP2 brings together specialists from a range of disciplines who are all driven by the same goal of improving understanding of the genetic architecture of Parkinson’s disease. Find out more about the GP2 working groups below.
Complex Disease Network
The Complex Disease Network, led by Andrew Singleton, coordinates the complex arm of GP2, comprised of the Cohort Integration and Data Analysis working groups.
The Monogenic Hub, led by Christine Klein, Katja Lohmann, and Niccolo Mencacci, is comprised of the Sample Prioritization, Data Analysis, and Portal Development working groups, and studies patients and families with a mutation in a single gene causing Parkinson's disease.
Complex Disease - Cohort Integration Working Group
The Cohort Integration working group, led by Huw Morris, assembles clinical and genetic data from new and existing cohorts for analysis to understand risk factor genes.
Monogenic - Sample Prioritization Working Group
The Sample Prioritization working group, led by Christine Klein and Kishore Kumar, prioritizes samples based on the input from the monogenic portal.
Complex Disease - Data Analysis Working Group
The Data Analysis working group, led by Mike Nalls, manages the maintenance, democratization, and acceleration of analyses, and provide analytical support for investigators with approved projects.
Monogenic - Data Analysis Working Group
The Data Analysis working group, led by Peter Heutink, carries out core analyses to identify the genetic basis of monogenic forms of Parkinson’s disease.
Data and Code Dissemination Working Group
The Data and Code Dissemination working group, led by Bradford Casey, works to enable open science by sharing meaningful data, analytical code, and results.
Monogenic - Portal Development Working Group
The Portal Development working group, led by Enza Maria Valente and Shen-Yang Lim, created, and runs the Monogenic Portal.
Underrepresented Populations Working Group
The Underrepresented Populations working group, led by Ignacio 'Nacho' Mata, facilitates increased representation, and analysis of the genetic factors associated with Parkinson's disease in non-European populations.
Operations and Compliance Working Group
The Operations and Compliance working group, led by Tatiana Foroud, facilitates sharing of GP2 data and samples through developing resources, tools, and templates.
Training, Networking and Communication Working Group
The Training, Networking and Communication working group, led by Alastair Noyce, promotes training, networking, and communication throughout the GP2 project.