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100,000 Participants and Counting – Massive Global Genetic Dataset Powers Discoveries in Parkinson’s Disease

December 1, 2025

Researchers have reached a major milestone in the effort to understand and treat Parkinson’s disease: more than 100,000 DNA samples from study participants around the world have now been genotyped and sequenced through the Global Parkinson’s Genetics Program (GP2).

Scientists Discover How PINK1 Pathway Activates to Protect Cells

Read this article to see how ASAP Team Alessi uncovered the mechanisms behind the activation of the PINK1 protein, an enzyme that protects the brain against nerve cell degeneration and the development of Parkinson’s disease.

June 18, 2024

Team Alessi

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Structures of Parkinson’s Disease-Linked Proteins Offer a Framework for Understanding How They Work Together

This story discusses Team Alessi’s research at St. Jude Children’s Research Hospital that used cryo-electron microscopy to characterize the interaction of two proteins implicated in Parkinson’s disease.

December 21, 2023

Team Alessi