Immune Cells May Lead to More Parkinson’s Cases in Men
New research from Team Sulzer reveals how a protein in brain cells may drive Parkinson’s onset—and offers a possible explanation for why Parkinson’s is much more common in men.
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April 28, 2026
ASAP and MJFF announced $261 million in new grant funding for the Collaborative Research Network (CRN) to map the biological blueprint of Parkinson’s disease and build a standardized toolkit of global research resources that are needed to turn discoveries into treatments.
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New research from Team Sulzer reveals how a protein in brain cells may drive Parkinson’s onset—and offers a possible explanation for why Parkinson’s is much more common in men.
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This story reports on new findings from Team Sulzer that indicates that PD begins in the gut and that what triggers initial gastrointestinal changes in Parkinson’s could be a misdirected immune attack.
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Team Sulzer used a mouse model of Parkinson’s disease to show that border-associated macrophages — not microglia — mediate the neuroinflammatory response in the brain.
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