Immune Cells May Lead to More Parkinson’s Cases in Men
New research from Team Sulzer reveals how a protein in brain cells may drive Parkinson’s onset—and offers a possible explanation for why Parkinson’s is much more common in men.
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100,000 Participants and Counting – Massive Global Genetic Dataset Powers Discoveries in Parkinson’s Disease
December 1, 2025
Researchers have reached a major milestone in the effort to understand and treat Parkinson’s disease: more than 100,000 DNA samples from study participants around the world have now been genotyped and sequenced through the Global Parkinson’s Genetics Program (GP2).
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Study Adds to Evidence That Parkinson’s Starts in the Gut
This story reports on new findings from Team Sulzer that indicates that PD begins in the gut and that what triggers initial gastrointestinal changes in Parkinson’s could be a misdirected immune attack.
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Parkinson’s Disease: Essential Role in Neuroinflammation Found for a Subset of Brain Macrophages
Team Sulzer used a mouse model of Parkinson’s disease to show that border-associated macrophages — not microglia — mediate the neuroinflammatory response in the brain.
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