Assembly and Use of High Density Silicon Electrophysiology Probes
Output Details
Description
This protocol describes the (1) assembly and (2) use of high-density silicon-based electrophysiological probes in mice. In our lab, this entails use of devices from Cambridge Neurotech, with 3D-printed and machined parts that are used to protect, mount, and secure the device on the mouse's head. Awake-behaving recordings can be made in the behavioral apparatus (eg open field, operant box, other assay) using a variety of recording setups, but here we describe recordings using an Intan-based electrophysiology system.
Identifier (DOI)
10.17504/protocols.io.36wgq641ylk5/v1
