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Collection of protocols for “PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection”
Output Details
Description
This a collection of protocols for "A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal microbial infection in a PINK1 KO mouse model of Parkinson’s disease". In this GI-targeted pathogen-induced PD mouse model systems (PINK1 KO mice with gram negative bacterial infections) we found that T cells are a major player in driving PD-like motor symptoms at late stages following infection.
Identifier (DOI)
10.17504/protocols.io.kxygxy77ol8j/v1