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Dendritic Spine Analysis

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Haloperidol is reported to induce a series of homeostatic synaptic and intrinsic adaptations primarily in the indirect pathway circuits. These adaptations include dendritic spine loss in iSPNs, which occurs after 5 days and persists for up to 14 days of daily treatment. We examined the haloperidol-induced dendritic spine density patterns in iSPNs after 7 days of treatment

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Aligning Science Across Parkinson's
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