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Differential response of α-synuclein expression to bacterial ligands and metabolites in mouse enteroendocrine cells
Output Details
- 2D cultures
- Alpha-synuclein
- Gut
Meet the Authors
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Hervé Blottiere, PhD
Collaborating PI: Team Schapira,
National Research Institute for Agriculture, Food and Environment
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Related Research
α-Synuclein expression in response to bacterial ligands and metabolites in gut enteroendocrine cells – an in vitro proof of concept study
Caudo-rostral migration of pathological forms of α-synuclein from the gut to the brain is proposed as an early feature in Parkinson disease pathogenesis, but the underlying mechanisms remain unknown. Intestinal epithelial enteroendocrine cells…
Datasets and Key Resources Table used in Do, Quyen B. et al. (2023) “Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation”
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