Direct visualisation of alpha-synuclein oligomers in human brain tissue – Raw Data
By Rebecca Andrews, PhD, Joanne Lachica, MD, Christina Toomey, PhD, Jonathan Breiter, MSc, Ru Tian, MD, Joseph Beckwith, PhD and Steven Lee
Output Details
Description
Direct visualisation of alpha-synuclein oligomers in human brain tissue - Raw Data
Identifier (DOI)
10.5281/ZENODO.10610924
Tags
- Alpha-synuclein
- Confocal microscopy
- Human
- Microscopy - optical
- Oligomer
- Post-mortem brain tissues
- Postemortem
Meet the Authors
Related Research
Direct visualisation of alpha-synuclein oligomers in human brain tissue – Processed Data
Direct visualisation of alpha-synuclein oligomers in human brain tissue - Processed Data
Large-scale visualisation of α-synuclein oligomers in Parkinson’s disease brain tissue
ASA-PD (Advanced Sensing of Aggregates - PD) is a new imaging method to map α-synuclein oligomers in human brain tissue, revealing specific early proteinopathy markers in PD patients. This may aid in understanding disease mechanisms.
Cryo-EM map of in vitro grown G14R alpha-synuclein fibrils
3.0 A resolution cryo-EM map obtained from recombinant a-synuclein fibrils carrying the G14R mutation recently discovered in a patient of a complex neurological disease.