ASA-PD (Advanced Sensing of Aggregates - PD) is a new imaging method to map α-synuclein oligomers in human brain tissue, revealing specific early proteinopathy markers in PD patients. This may aid in understanding disease mechanisms.
3.0 A resolution cryo-EM map obtained from recombinant a-synuclein fibrils carrying the G14R mutation recently discovered in a patient of a complex neurological disease.
