Lentiviral vector plasmid for overexpression of ATP10B (R153X)

By Chris Van den Haute, PhD and Peter Vangheluwe, PhD

Output Details

Description
Lentiviral vector plasmid for overexpression of ATP10B (R153X) validated for use in cell culture
Team
Team Vangheluwe
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

Related Research

The lipid flippase ATP10B enables cellular lipid uptake under stress conditions

ATP10B mutations are linked to Parkinson's and Lewy body disease. ATP10B acts as a lipid transporter in late endo-/lysosomes, enhancing phosphatidylcholine uptake in cells under stress conditions like rotenone treatment.

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Plasmid construction – Chen et al. 2025 NSMB

Standard cloning procedure.

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Image Processing and 3D Reconstruction – Chen et al. 2025 NSMB

Image processing and 3D reconstruction applied in Chen et al. 2025 NSMB

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