Microscopy dataset for: Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons
By onImaging dataset for the manuscript "Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons ", by Belfort, Jia et al., 2024.
Immunohistochemistry of free floating slices
By onThis protocol details the immunohistochemistry of free floating slices.
DAB Immunohistochemistry (IHC) Staining for Stereological Analysis
By onThis protocol details the DAB immunohistochemistry staining for stereological analysis of 40 µM slices cut with cryostat and stored in antifreeze.
Data associated with “Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables delivery of large genetic cargo”
By onTabular data associated with the publication "Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables delivery of large genetic cargo"
Confocal imaging of transcriptional crosstalk between AAV genomes carrying different enhancers in the mouse brain
By onA data collection of images of brains of mice transduced with viral vectors carrying different regulatory elements and reporters to study transcriptional crosstalk between AAV genomes
Additional data repository for the study of Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
By onZip file 1: astrocytes calcium data measured using Fura 2 Zip file2: astrocytes ROS measured using DHE (Dihydroethidium) Zip file 3: astrocytes cell death measured using Sytox green
A data repository for the study of Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
By onA data repository for the study of Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
Raw files for Part3: Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
By onAll data presented in Figure 6
Immunofluorescence source data
By onThese files include the raw, unedited, immunofluorescence images.
Sparse labeling-enabled confocal imaging of dendritic spines followed by analysis
By onThis protocol describes procedures starting from sparsely labelling neurons to analyzing their dendritic spines, including stereotaxic injection, brain perfusion and fixation, sectioning and mounting, confocal imaging and spine reconstruction.
Ex vivo imaging of genetically encoded sensors with two-photon laser scanning microscopy (2PLSM)
By onThis protocol has been adapted for imaging genetically encoded sensors (e.g. GRABACh3.0) in ex vivo brain slices with two-photon laser scanning microscopy (2PLSM).
Ex vivo imaging of dendritic calcium transients and spines with two-photon laser scanning microscopy (2PLSM)
By onThis is an adapted protocol for imaging dendritic Ca2+ transients and dendritic spines of striatal spiny projection neurons (SPNs) in ex vivo brain slices with two-photon laser scanning microscopy (2PLSM).
GRAB Acetylcholine (ACh) sensor imaging in ex vivo mouse striatal slices
By onProtocol for imaging GRAB Acetylcholine (ACh) sensor in mouse striatal slices and measuring changes in fluorescence signals due to ACh release is described.
Zhai et al. 2025 Data files
By onData used to generate figures in the manuscript "State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson's disease" by Zhai et al.
Immunohistology for Mouse Brain Sections
By onThis protocol outlines the general steps for preparing mouse brain tissue for immunostaining and histology analysis in the Ding lab.
Immunohistochemistry (Brain organoids)
By onProtocol for preparing brain organoid slides and performing immunostainings to analyze protein expression and localization in the 3D model.
Raw images of SNr molecular anatomy
By onRaw images associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.
Quantification tables of SNr molecular organization
By onConfocal image quantification tables associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.
Data for Jain et al Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine
By onPrimary data for Jain et al "Adaptor protein-3 produces synaptic vesicles that release phasic dopamine" (Proc Natl Acad Sci. 2023; 120(42):e2309843120. doi: 10.1073/pnas.2309843120)
