Key Resouce Table (KRT) & Numerical data used in “AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact”
By onKey Resource Table (KRT) detailing quantitative data, code, protocols, and key lab materials used in "AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact".
BenPadman/AIVE: AIVE release 1_Basic scripts and macros for implementing AIVE: AI-directed Voxel Extraction.
By onBenPadman/AIVE: AIVE release 1
EMPIAR-12885 Datasets associated with AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact
By onCollection of datasets used in "AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact"
General descriptors of calcium activity in M1 and SMA cells
By onCalcium event rates, IEI CV, and event amplitude were measured in SMA and M1 cells during spontaneous or reaching tasks to analyze neural activity.
Calcium imaging in SMA and M1 of macaques
By onCalcium imaging with miniature microscopes reveals neuron activity patterns in deep layers of SMA and M1, showing synchronous activity and sequential activation.
Live-cell Imaging of Mitochondrial Membrane Proteins in Cultured Mammalian Cells by Airyscan Laser Scanning Confocal microscopy
By onThis is a protocol for live-imaging of cultured mammalian cells transfected with plasmids encoding fluorescently-tagged mitochondrial proteins.
In situ Cryo ET data collection and processing with Scipion
By oncryo et data collection and subtomogram averaging using Scipion
Zhai et al. 2025 Raw data
By onData includes immunohistochemistry images, two-photon images of patched neurons, whole-cell recordings for somatic excitability and Sr2+-oEPSC, spine density imaging, ACh sensor imaging, and dendritic excitability linescan data.
Jaccard (coactivation) analysis outputs
By onJaccard values for calcium transients in M1 and SMA of macaques during spontaneous or task reaching behavior.
Part2 Raw data for: Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease
By onThe raw data for Figure 6 in the manuscript supports the role of lysosomal glucocerebrosidase in ciliary Hedgehog signaling, linking it to Parkinson's disease.
Part1 Raw data for: Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson’s disease
By onRaw data for Figures 1-5 in a study on the role of lysosomal glucocerebrosidase in ciliary Hedgehog signaling, linking to Parkinson's disease.
Data related to “Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy”
By onData related to "Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy"
Original data for Figures 1-7 & Figure EV1-EV4A [Hanna et al. 2024]
By onOriginal data for Figures 1-7 & Figure EV1-EV4A from Hanna et al 2024
RNA scope for ATP10b
By onProtocol for RNAscope® in situ hybridization on fixed-frozen mouse brain tissue using the RNAscope® Multiplex Fluorescent v2 kit. Includes staining steps for dorsal striatum, sample preparation, and cryosectioning.
Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery
By onThis Zenodo deposit is a collection of Microscopy data, KRT, Read me Files associated with the publication "Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery" by Adriaenssens et al.
Confocal microscopy to assess TelC and iGluSnFR expression in fixed mouse brain slices
By onProtocol outlines tissue processing after glutamate recordings with iGluSnFR sensor & behavior experiments post TelC viral injection in dorsal medial striatum.
Micro-CT scanning for post-implant localization of multi-fiber arrays in mouse striatum
By onNew micro-fiber array allows chronic measurement and optogenetic manipulation at 100+ locations in mice, for studying cell-type and neurotransmitter-specific signals in 3-D volumes. Protocol involves micro-CT scanning and fiber localization.
LRRK2 regulates haloperidol mediated upregulation of immediate early genes in iSPNs
By onTo define the impact of LRRK2 kinase activity on the expression pattern of Nr4a1 mRNA in the SPNs, we used multicolored single-molecule fluorescence in situ hybridization
