Study adds to evidence that Parkinson’s starts in the gut
This story reports on new findings from Team Sulzer that indicates that PD begins in the gut and that what triggers initial gastrointestinal changes in Parkinson’s could be a misdirected immune attack.
Dopamine neurons may be more diverse than thought
Parkinson’s News Today discusses a cellular study of mice by Team Awatramani that found that a specific subset of dopamine-producing nerve cells in the brain appear to respond to movement acceleration and correspond with the region where cell death is particularly pronounced in PD.
Parkinson’s disease: Essential role in neuroinflammation found for a subset of brain macrophages
Team Sulzer used a mouse model of Parkinson’s disease to show that border-associated macrophages — not microglia — mediate the neuroinflammatory response in the brain.
Finding rewrites understanding into Parkinson’s disease pathway
This news story reports on a study by Team Hurley that solves a mystery about how the protein Optineurin recognizes unhealthy mitochondria “tagged” by PINK1 and Parkin, enabling their delivery to our body's garbage disposal system.
A Parkinson’s ‘game changer,’ backed by Michael J. Fox, could lead to new diagnostics and, someday, treatments
STAT highlights how The Parkinson’s Progression Markers Initiative (PPMI) recently discovered how αSyn-SAA could be a novel tool for precision medicine approaches, earlier intervention, and improved clinical trial design for Parkinson's disease.
Red/yellow brain pigment linked to Parkinson’s disease: Study
This story discusses a study by Team Chen that found that people with Parkinson’s disease have higher than normal levels of a nerve cell-damaging red/yellow pigment called pheomelanin in their substantia nigra, the area of the brain that’s mainly affected by the neurodegenerative disease.
