Raw files for Part3: Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

By Enrico Bagnoli, PhD, Yu-En Lin, PhD and Sophie Burel
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Output Details

Description
Raw data associated with Figure 6: "Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain" publication.
Tags
  • Microscopy - optical
  • Mouse
Team
Team Alessi
Program
Collaborative Research Network
Theme
PD Functional Genomics

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Related Research

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

Mutations in LRRK2 and PINK1 are linked to Parkinson’s disease. Loss of PINK1 doesn't affect LRRK2-mediated Rab phosphorylation. Both genes impair ciliogenesis through parallel pathways, suggesting a common therapeutic strategy for PD.

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Quantification tables of SNr molecular organization

Confocal image quantification tables associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.

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Raw images of SNr molecular anatomy

Raw images associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.

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