The impact of MG149, a KAT8 inhibitor, on mitophagy: cell-based in vitro assays

By Capucine de Talhouet, MSc, Benjamin O’Callaghan, PhD, Noemi Esteras, Marc P.M. Soutar and Helene Plun-Favreau, PhD
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Output Details

Description
This protocol describes a set of mitophagy-related cell-based in vitro assays used (ex: TMRM, mitoKeima) to evaluate the functional significance of MG149 and KAT8 inhibition.
Identifier (DOI)
10.17504/protocols.io.eq2ly7m8qlx9/v2
Tags
  • Activity Assay
  • Cell biology
  • Cell culture
  • Mitophagy
  • PINK1
Team
Team Hardy
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

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    Capucine de Talhouet, MSc

    Key Personnel: Team Hardy, 

    University College London

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    Benjamin O’Callaghan, PhD

    Key Personnel: Team Hardy, 

    University College London

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    Noemi Esteras

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    Marc P.M. Soutar

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    Helene Plun-Favreau, PhD

    Collaborating PI: Team Hardy, 

    University College London

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