This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Characterizing Parkinson’s Disease Clinical and Biomarker Interactions in REM Sleep Behavior Disorder
Output Details
Description
Hyposmia was strongly associated with reductions in striatal dopaminergic activity and α-syn SAA positivity. MDS Prodromal PD Probability Scores, which incorporate DaT and olfactory function, predicted SAA positivity and phenoconversion. Among six phenoconverters (RBD-PC), DaT positivity was much more common (80%) than in non-phenoconverters (10%), but no significant motor or non-motor symptom differences were observed between the two groups at baseline, likely due to the small sample size.
Identifier (DOI)
10.1101/2025.05.16.25327469