Aggregation of human recombinant alpha-synuclein

By Minee Choi, PhD
View Published Protocol

Output Details

Description
This protocol describes a method of generating aggregation of human recombinant alpha-synuclein.
Identifier (DOI)
10.17504/protocols.io.6qpvr35obvmk/v1
Tags
  • Aggregation
  • Alpha-synuclein
  • Human
  • Protein aggregates
Team
Team Wood
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

  • Minee Choi, PhD

    Key Personnel: Team Wood, 

    The Francis Crick Institute

Related Research

Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology

The results identify neurons vulnerable to Lewy pathology in the PD cortex and identify a conserved signature of molecular dysfunction in both mice and humans.

View Article

fcs files to “The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model”

Dataset associated with DOI: 10.17617/3.51VXU0

View Dataset

The emerging role of LRRK2 in tauopathies

Parkinson’s disease (PD) is conventionally described as an α-synuclein aggregation disorder, defined by Lewy bodies and neurites, and mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common autosomal dominant cause of PD. However,…

View Article
View More Outputs
Aligning Science Across Parkinson's
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.