Brain slice physiology and optogenetics

By Hong-Yuan Chu, PhD
View Published Protocol

Output Details

Description
This protocol describes Chu Lab's standard external solutions for electrophysiology.
Identifier (DOI)
10.17504/protocols.io.eq2ly7m2rlx9/v1
Tags
  • Electrophysiology
Team
Team Wichmann
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

Related Research

Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation

Our results documented motor cortical neuronal hyperexcitability associated with αSyn aggregation and provided a novel mechanistic understanding of cortical circuit dysfunction in PD

View Article

Ex Vivo Electrophysiology V2 – Alternate version of Nelson lab protocol

This protocol describes preparation of brain slices, setup of electrophysiology rig, and solutions for collecting whole cell and cell attached recordings.

View Protocol

Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories

Auditory and temporal cortexes send strong excitatory signals to substantia nigra pars lateralis dopamine neurons, impacting threat conditioning. Inhibiting this pathway impairs memory retrieval, revealing its role in threatening behaviors.

View Article
View More Outputs
Aligning Science Across Parkinson's
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.