Key Personnel: Team Harper,
Harvard University
Lead PI (Core Leadership): Team Harper,
Homozygous mutations of granulin precursor (GRN) lead to neuronal ceroid lipofuscinosis1, a severe neurodevelopmental disease, in humans and neuroinflammation in mice2. Haploinsufficiency of GRN almost invariably causes frontotemporal dementia…
Describes sample preparation procedure for Quantitative Whole Cell Proteome Analysis by Mass Spectrometry
Protocol for immunocytochemistry on mammalian cells in 24 and 96 well plates.
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