The secretion of endogenous α-syn mediated by DNAJC5 is found in a human neuroblastoma cell line, The authors propose that DNAJC5 forms a palmitoylated oligomer to accommodate and export α-syn.
Version: 2.0.0
Release Date: December 11, 2024
This release notes document provides a concise overview of the updates and enhancements introduced in Version 2.0.0 of the CRN Cloud platform.
We modelled extracellular diffusion in super-resolved images of live brain tissue neuropil. We found that extracellular space geometry shapes local diffusion and this has functional implications for signaling arising from synaptic spill-over.