Protocol details surgical steps for viral injections and optical fiber implantation in mouse striatum to monitor neurotransmitter dynamics during learning and extinction, using genetic sensors and tetanus toxin to suppress acetylcholine release.
This protocol details standard operating procedure (SOP) for systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in non-human primates.
This protocol includes the stereotaxic viral injections and array implantation steps using a micro-fiber array approach that measures and optogenetically manipulates local dynamics across multiple targeted locations simultaneously in behaving mice.
