metabolomics data related to “Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease”

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Output Details

Description
The metabolomics is submitted at the NIH Common Fund’s National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org where it has been assigned Project ID (PR001491). The data can be accessed directly via its Project DOI: (https://doi.org/10.21228/M80M7R).
Identifier (DOI)
10.21228/M80M7R
Tags
  • Metabolomics
Team
Team Vangheluwe
Program
Collaborative Research Network
Theme
PD Functional Genomics

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Disruption of lysosomal proteolysis in astrocytes facilitates midbrain proteostasis failure in an early-onset PD model

Accumulation of advanced glycation end products (AGEs) on biopolymers accompany cellular aging and drives poorly understood disease processes. Here, we studied how AGEs contribute to development of early on-set Parkinson’s Disease (PD) caused by…

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