This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.
Datasets associated with “Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology”
Output Details
- Antemortem
- Cholinergic neurons
- Dopaminergic neurons
- Enteric nervous system
- In Vivo
- Metabolomics
- Metagenome
- Microbiome
- Mouse
- Proteomics
- RNA bulk
Meet the Authors
-
Bryan B. Yoo
-
Peter Thuy-Boun
-
Kelly Weldon
-
Collin Challis
-
Michael J. Sweredoski
-
Ken Y. Chan
-
Taren M. Thron
-
Gil Sharon
-
Annie Moradian
-
Gregory Humphrey
-
Qiyun Zhu
-
Justin Shaffer
-
Dennis W. Wolan
-
Pieter C. Dorrestein
-
Rob Knight
-
Viviana Gradinaru, PhD
Lead PI (Core Leadership): Team Gradinaru,
California Institute of Technology
-
Sarkis Mazmanian
Co-PI (Core Leadership): Team Sulzer, Team Gradinaru,
California Institute of Technology
-
Related Research
Peripheral neuronal activation shapes the microbiome and alters gut physiology
The authors specifically activate ChAT- or TH-expressing gut-associated neurons in mice and perform multi-omics, finding that subsets of peripherally-activated neurons differentially regulate the gut microbiome and host GI physiology.
WGS data related to “Is Gauchian genotyping of GBA1 variants reliable’
Gauchian software helps identify GBA1 variants but struggles with rare ones due to database limitations, impacting diagnostic accuracy. Data from this study will aid future research on GBA1 variants.
Stereotaxic Surgery
This protocol describes the steps for performing mouse stereotaxic surgery. It is applicable to intracranial injections of viruses and drugs.