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The Initiative

Aligning Science Across Parkinson’s (ASAP) is a global research initiative changing the way science is typically done. With input across sectors and disciplines, we are creating collaborative and transparent research processes in an environment that can drive discoveries for Parkinson’s disease research.

Our initiative is different from traditional funding programs due to our ability to make large, long-term commitments, our appetite for risk and ability to support studies that might otherwise not be funded, and our steadfast belief that we can accelerate advances by fostering a collaborative and open approach to research through our open science policies.

ASAP’s mission is to accelerate the pace of discovery and inform the path to a cure for Parkinson’s disease (PD) through collaboration, research-enabling resources, and data sharing.

ASAP Theory of Change

At ASAP, we apply a Theory of Change framework, which allows us to cohesively and comprehensively measure progress – from idea to result – in the context of our overarching vision. Further, it enables us to reflect upon and iterate processes as we measure our progress to date. Our work is broken down into the three main components of our mission: collaboration, resource generation, and data sharing, which underpin our strategies for accelerating discoveries for Parkinson’s disease.

SUPPORT COLLABORATION

Scientific progress can be accelerated when researchers exchange ideas early and often, in a collaborative rather than competitive manner.

GENERATE RESOURCES

By supporting resource development, we are building an infrastructure, available to the larger scientific community, that improves access to research tools, reproducibility of studies, and process efficiency to accelerate discoveries.

SHARE DATA

Sharing research outputs, such as datasets, code, and protocols, enables scientists to build upon each other’s work. This approach fosters collaboration, attracts new talent and expertise to the field, and increases the statistical power of research through meta-analysis.

ACCELERATE DISCOVERIES

We believe that by supporting collaboration, generating resources, and creating a culture of data sharing, we can deliver faster and better outcomes for Parkinson’s disease research.

The Road to ASAP

Starting in 2017, we convened more than 100 multidisciplinary experts and strategists to shape ASAP’s strategic roadmap and thoughtfully guide our future investments in Parkinson’s disease research. Learn more about our journey and impact to date.

Our Management Organization

Coalition for Aligning Science, an organization with a track record for designing and implementing large-scale biomedical research programs to accelerate discoveries, serves as the managing entity, setting the strategy and vision for the ASAP initiative.

Our Implementation Partner

The Michael J. Fox Foundation for Parkinson’s Research (MJFF), a nonprofit, with a track record for operational excellence and commitment to accelerating the next generation of Parkinson’s disease treatments, serves as the implementation partner.

Executive Leadership

Managing Director

Aligning Science Across Parkinson's (ASAP)
Coalition for Aligning Science (CAS)
USA

Deputy Director,

Aligning Science Across Parkinson's (ASAP)
Coalition for Aligning Science (CAS)
USA

Managing Portfolio Director

Aligning Science Across Parkinson's (ASAP)
Coalition for Aligning Science (CAS)
USA

Current Scientific Advisory Board

Chair of the Scientific Advisory Board, University of California at Berkeley & Howard Hughes Medical Institute | USA
Harvard University | USA
Nexus NeuroTech | USA
Scripps Research Institute | USA
Harvard Medical School | USA
Stanford University | USA
YaghPenn Consulting, BV | Belgium
Allen Institute | USA

Partners

Planning Advisory Council

With thanks to ASAP’s founding Advisory Council for their input and guidance in developing the strategic roadmap.

James Beck, PhD
Chief Scientific Officer, VP, Scientific Affairs, Parkinson’s Foundation

Patrik Brundin, MD, PhD
Van Andel Research Institute Center for Neurodegenerative Science

Pietro De Camilli, MD
Kavli Institute for Neuroscience at Yale School of Medicine

Marie-Françoise Chesselet, MD, PhD
Van Andel Institute Center for Neurodegenerative Science

Martin Citron, PhD
UCB Pharma

David Dexter, PhD
Parkinson’s UK, Imperial College London

Ted Dawson MD, PhD
Johns Hopkins University School of Medicine

Thomas Gasser, MD, PhD
Hertie Institute for Clinical Brain Research

Magali Haas, MD, PhD
Cohen Veterans Bioscience

Karl Kieburtz, MD, MPH
University of Rochester Medical Center

Walter Koroshetz, MD
National Institute of Neurological Disease and Stroke

Robert Malenka, MD, PhD
Stanford University School of Medicine

Kelsey Martin, MD, PhD
David Geffen School of Medicine at UCLA

Eliezer Masliah, MD
National Institute of Aging, NIH

K. Kimberly McCleary
The Kith Collective

Karoly Nikolich, PhD
Alkahest

C. Warren Olanow, MD
Mt. Sinai School of Medicine

Bernardo Sabatini, MD, PhD
Harvard Medical School

Randy Schekman, PhD
University of California, Berkeley

Darryle Schoepp, PhD
Merck

Todd Sherer, PhD
The Michael J. Fox Foundation for Parkinson’s Research

Andrew Singleton, PhD
Global Parkinson’s Genetics Program (GP2)

Beth Stevens, PhD
Harvard Medical School

David Sulzer, PhD
Columbia University Medical Center

Huda Zoghbi, MD
Baylor College of Medicine

Our Research Community

ASAP supported programs are designed to help implement our vision. Together, our shared commitment to understanding the root causes of Parkinson’s disease is accelerating discovery.

Aligning Science Across Parkinson's
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