Dr. Hollis Cline is the Chair and Hahn Professor of Neuroscience at The Scripps Research Institute. Her research aims to identify the mechanisms by which brain activity affects brain structure and function over the lifespan. Her studies have used several experimental systems, including Xenopus and rodent visual systems and hiPSC-derived neural cells to increase understanding of mechanisms controlling neurogenesis, synapse formation, loss and plasticity, structural dynamics of neurons, and the assembly/disassembly of functional circuits. Cline’s research has led to the discovery that neuronal activity regulates visual system development, plasticity, and recovery from injury through coordinated mechanisms, affecting neuronal structure, synaptic function, and activity-induced protein synthesis. Cline’s studies have relevance to a variety of developmental neurological and neurodegenerative disorders.
Dr. Cline received her PhD in Neurobiology from the University of California, Berkeley, followed by postdoctoral training at Yale with Dr. Martha Constantine-Paton and at Stanford with Dr. Richard Tsien. Cline joined Scripps Research in 2008 after 14 years at Cold Spring Harbor Laboratory, where she was the Professor of Neuroscience and the Director of Research. Dr. Cline has received numerous awards and is a fellow of the American Association for the Advancement of Science and a member of the U.S. National Academy of Sciences and the American Academy of Arts and Sciences.