Drd1-T2A-Cre mouse line

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Output Details

Description
Dopamine D1 receptor cre knock in mouse line generated by the Costa lab. The gRNA to mouse Drd1 gene, the donor vector containing "T2A-Cre" cassette, and Cas9 mRNA were co-injected into fertilized mouse eggs to generate targeted knock-in offspring. F0 founder animals were identified by PCR followed by sequence analysis, which were bred to wildtype mice to test germline transmission and F1 animal generation.
Tags
  • Dopamine
  • Mouse
  • Mouse model
Team
Team Surmeier
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

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Drd1-T2A-FlpO Mouse Line

Dopamine D1 receptor FlpO mouse line generated by the Costa lab at Cyagen using CRISPR/Cas-mediated genome engineering.

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View More Outputs
Aligning Science Across Parkinson's
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