Tabular datasets for “A role for the subthalamic nucleus in aversive learning”
By onTabular datasets for "A role for the subthalamic nucleus in aversive learning." Includes FISH, electrophysiological, and behavioral datasets.
Isolation of mouse midbrain, RNA purification, reverse transcription, and quantitative PCR
By onProtocol for dissection of midbrain from mice, followed by isolation of RNA from midbrain samples, reverse transcription of mRNA to cDNA, and quantitative real-time PCR for analysis of VMAT2 expression levels.
Mechanisms and clinical implications of gut-brain interactions
By onResearch in the past decade has shed light on the gut-brain connection, revealing its role in disease and therapeutics. Targeting gut-brain pathways shows promise for therapeutic benefits.
Regulator of G protein signaling 10: a critical regulator of chronic systemic inflammation in parkinson’s disease
By onThe inflammatory response must be regulated to avoid chronic systemic inflammation. Imbalance can lead to diseases like Parkinson's. The review explores the link between inflammation, Parkinson's, and the role of RGS10 in regulating inflammation.
Striatal dopamine signals internal states related to behavioral performance over prolonged timescales in monkeys
By onDopamine plays dual roles in behavior: fast reward prediction errors and slow motivational states. Dopamine release in monkeys' brain regions tracks performance changes, suggesting a single signal for both functions.
Datasets for Murray et al. 2026 (Prolonged Timescales) Manuscript
By onTrial information, dopamine data, and autonomic/behavioral data used for the prolonged timescales Murray et al. 2026 manuscript
Neural Control of Autonomic Arousal During Threat Anticipation Revealed by High-Resolution Cardiac Contractility
By onThese findings highlight neural correlates of adaptive behavioral mobilization during emotion-guided action, shedding light on motor circuitry that may be engaged during paradoxical kinesia, a phenomenon of emotion-relevant motor facilitation in PD.
Code for Murray et al. 2026 (Prolonged Timescales) Manuscript
By onSource code to replicate core analyses used throughout the Murray et al. 2026 (Prolonged Timescales) manuscript.
Data and code for Stasiak et al. 2026 (TREV-Emotion) Manuscript
By onOnline repository for the data and scripts used in the Stasiak et al., 2026 preprint on TREV-derived cardiac contractility in threat anticipation contexts.
Protocol for Stasiak et al. 2026 (TREV-Emotion) Manuscript
By onProtocol for Stasiak et al. 2026 (TREV-Emotion) Manuscript. Describes participant preparation, shock calibration, scan sequence, active escape task, and participant debriefing.
Distinct amygdalar pathways to frontopolar cortex and medial temporal lobe support temporal memory for emotional events
By onAmygdala pathways shaped temporal memory for emotional images, some sharpening it, others blurring it. Since related circuits drive paradoxical kinesia in PD, our findings may explain memory and cognitive decline in PD dementia.
Opto-Open Field Test
By onProtocol for optogenetic open field test, which records mouse behavior in an open field arena in response to alternating 5-minute periods of optogenetic stimulation.
Stereotaxic virus injection and fiber optic probe implantation
By onThis protocol serves to prepare mice for in vivo optogenetic stimulation.
Opto-Avoidance-EPM Test
By onThe Opto-Avoidance-Elevated Plus Maze test assesses the effect induced by photostimulation compared to a mouse's natural aversion to open areas.
Opto-RT-CPP Test
By onProtocol for Opto-RT-CPP (Optogenetic Real-Time Conditioned Place Preference) test. This test measures location preference or avoidance in response to optogenetic stimulation.
Opto-Negative Reinforcement Paradigm (Opto-NR)
By onProtocol for Opto-Negative Reinforcement paradigm (Opto-NR). This test uses an operant conditioning box with two nose-poke devices to test aversive learning in mice.
Sugar Positive Reinforcement Paradigm (Sugar-PR)
By onProtocol for Sugar Positive Reinforcement Paradigm (Sugar-PR) with optogenetic stimulation.
Post-injection Histological Analysis
By onProtocol for post-injection histological analysis following optogenetic behavioral assays.
Excitatory synaptic structural abnormalities produced by templated aggregation of α-syn in the basolateral amygdala
By onPD and DLB involve α-syn inclusions in the amygdala affecting cognition and emotions. Cortico-amygdala synapses with α-syn aggregates show increased volume of synapses, potentially contributing to behavioral impairments.
