Histology Fushiki et al 2024
By onHistology protocol for Fushiki et al 2024 , to quantify Th+ cells and visualize the dorsal-tier or ventral-tier of SNc DANs.
Open Field & Cylinder test Behavior Assays
By onProtocols for mouse behavioral studies using the open field test and the cylinder test from Fushiki et al 2024.
Single-cell RNA-sequencing data from A Vulnerable Subtype of Dopaminergic Neurons Drives Early Motor Deficits in Parkinson’s Disease
By onSingle-nucleus RNA profiling of the ventral midbrain of MitoPark mice, their littermate controls and C57BL/6 mice at 8, 16, and 24 weeks of age (8 mice in each group; 4 males and 4 females).
Non-human Primate Arm-reaching Behavioral Tasks
By onProtocol for training and testing non-human primates in arm-reaching tasks to evaluate parkinsonian animals
Specific cell states underlie complex tissue regeneration in spiny mice
By onThis paper compares regenerative and fibrotic healing to identify injury-induced cell states associated with persistent cell cycle progression and complex tissue regeneration in mammals.
Key Resource Table for Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
By onComprehensive key resource table for the publication: "Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses", Mendelsohn et al 2025.
SNr subpopulation neuroanatomy-code
By onMatlab scripts used to plot anatomical data related to the study: Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.
Quantification tables of SNr molecular organization
By onConfocal image quantification tables associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.
Raw images of SNr molecular anatomy
By onRaw images associated with the manuscript Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses.
Data for Jain et al Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine
By onPrimary data for Jain et al "Adaptor protein-3 produces synaptic vesicles that release phasic dopamine" (Proc Natl Acad Sci. 2023; 120(42):e2309843120. doi: 10.1073/pnas.2309843120)
Slow Release Pellet Implantation
By onThis protocol describes how to subcutaneously implant slow-release pellets into mice.
Striatal Punch Collection
By onThis protocol describes how to collect striatal punches from fresh frozen mouse brain tissue for HPLC analysis.
Stereotaxic intracranial virus injection in mice
By onThis protocol outlines steps for conducting stereotaxic brain injections of virus in mice in the Ding lab.
Immunohistology for Mouse Brain Sections
By onThis protocol outlines the general steps for preparing mouse brain tissue for immunostaining and histology analysis in the Ding lab.
Ex Vivo Mouse Brain Slice Whole-Cell Patch-Clamp Electrophysiology
By onThis protocol outlines steps for performing ex vivo slice whole-cell patch-clamp electrophysiology experiments, including voltage clamp and current clamp recordings as well as optogenetic stimulation in the Ding lab.
Stereotaxic Optic Fiber Implantation in Mice
By onThis protocol describes implantation of one or multiple optic fiber cannulae in mouse brains used for optical recording brain activity using fiber photometry or for optogenetic manipulation of neuronal activity in mice performing behavioral tasks.
Head-fixed Lever-pushing Task in Mice
By onThis protocol describes a head-fixed lever-pushing task used to study motor learning and memory in mice suitable for recording neuronal activity concurrently.
Head-fixed Locomotion Task in Mice
By onThis protocol describes a head-fixed locomotion task used to study motor learning in mice suitable for recording neuronal activity concurrently.
Accelerating Rotarod Task in Mice
By onThis protocol describes an accelerating rotarod task used to study motor learning in mice in the Ding lab.
Optogenetic Silencing of Projection Terminals
By onThis protocol describes the combination of protocols and techniques that are employed to optogenetically silence projections from various areas in the brain.
