all data related to “Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout”

By Camille Goldman, BSc
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Output Details

Description
Raw imaging data for "Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout"
Identifier (DOI)
10.17632/fmxdjgrjw5.1
Team
Team Vangheluwe
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

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    Camille Goldman, BSc

    Key Personnel: Team Vangheluwe, 

    Icahn School of Medicine at Mount Sinai

Related Research

Genetically Encoded and Modular SubCellular Organelle Probes (GEM SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN

Lysosomal and mitochondrial dysfunction are implicated in many diseases. GEM-SCOPe, a modular toolbox of fluorescent markers, helps visualize these organelles. In a PRKN-knockout model of PD, GEM-SCOPe identified disease-associated changes.

View Article

Plasmid construction – Chen et al. 2025 NSMB

Standard cloning procedure.

View Protocol

Image Processing and 3D Reconstruction – Chen et al. 2025 NSMB

Image processing and 3D reconstruction applied in Chen et al. 2025 NSMB

View Protocol
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