AT8 Tau Pathology Image Analysis

By Hemanth Ramesh Nelvagal, PhD, Toby Curless, MSc and Zane Jaunmuktane, MD
View Published Protocol

Output Details

Description
This protocol describes how to analyse AT8 tau pathology in human brain tissue (FFPE sections with IHC).
Identifier (DOI)
10.17504/protocols.io.n2bvj386wlk5/v1
Tags
  • Digital pathology
  • Formalin-fixed paraffin-embedded
  • Human brains
  • Immunohistochemistry
  • Pathology
Team
Team Hardy
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

Related Research

QSBB Digital Pathology Resource

This digital pathology resource contains digital whole slide images from Lewy body disorders: Parkinson’s disease, Parkinson’s disease with dementia, dementia with Lewy bodies, and control cases.

View Dataset

Formalin Fixed Paraffin Embedded (FFPE) Tissue Preparation for Digital Pathology Quantification Using QuPath

QuPath is an open-source digital pathology analysis software. Here, it is used to quantify various misfolded proteins across anatomical regions.

View Protocol

Dynamic basal ganglia output signals license and suppress forelimb movements

Basal ganglia is fundamental to motor control and dysfunction is linked to motor deficits. Our results demonstrate the existence and function of highly specific and temporally precise movement representations in basal ganglia output circuitry.

View Article
View More Outputs