Confocal imaging of transcriptional crosstalk between AAV genomes carrying different enhancers in the mouse brain

By Gerard Coughlin, BSc, Mate Borsos, Nathan Appling, Bre'Anna Barcelona, Acacia Mayfield, PhD, Elisha Mackey, Rana Eser, Cameron Jackson, Xinhong Chen, Spripriya Ravindra Kumar and Viviana Gradinaru, PhD
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Output Details

Description
This data collection contains images of brains of mice transduced with viral vectors carrying different regulatory elements and reporters to study transcriptional crosstalk between AAV genomes. The data is described in the publication "Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo."
Identifier (DOI)
10.35077/g.1163
Tags
  • AAV (Adenoassociated Virus)
  • Brain
  • Microscopy - optical
  • Mouse
  • Transcriptional regulation
Team
Team Gradinaru
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

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    Gerard Coughlin, BSc

    Key Personnel: Team Gradinaru, 

    California Institute of Technology

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    Mate Borsos

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    Nathan Appling

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    Bre'Anna Barcelona

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    Acacia Mayfield, PhD

    Key Personnel: Team Gradinaru, 

    California Institute of Technology

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    Elisha Mackey

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    Rana Eser

  • User avatar fallback logo

    Cameron Jackson

  • User avatar fallback logo

    Xinhong Chen

  • User avatar fallback logo

    Spripriya Ravindra Kumar

  • Viviana Gradinaru, PhD

    Lead PI (Core Leadership): Team Gradinaru, 

    California Institute of Technology

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