Generation of human-induced pluripotent-stem-cell-derived cortical neurons for high-throughput imaging of neurite morphology and neuron maturation

By Gautam Wali, PhD, Kwaku Dad Abu-Bonsrah, PhD, yan li, Deniz Kirik, MD, PhD, Clare Parish, PhD and Carolyn Sue, PhD
Published June 8, 2023
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Output Details

Published June 8, 2023

Description
A STAR protocol that describes how to differentiate cryopreserved human cortical neuronal progenitors into mature cortical neurons for high-throughput imaging analysis
Identifier (DOI)
10.1016/j.xpro.2023.102325
Tags
  • 2D cultures
  • Analysis
  • Imaging
  • Original Research
Team
Team Kirik
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

Related Research

Datasets and Key Resources Table used in Do, Quyen B. et al. (2023) “Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation”

The files found here are associated to Do, Q. et al (2023) study and contain: (a) all source and supplementary data, (b) Key Resources Table, and (c) list of primers.

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Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

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STC-1 cell culture

Cell culture of STC-1 mouse enteroendocrine cells.

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Aligning Science Across Parkinson's
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