PINK1: From Parkinson’s disease to mitophagy and back again

By Benjamin O’Callaghan, PhD, John Hardy, PhD and Helene Plun-Favreau, PhD
Published June 28, 2023
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Output Details

Published June 28, 2023

Description
This perspective discusses the implications of a 2010 PLOS Biology paper (https://doi.org/10.1371/journal.pbio.1000298) that shed light on the functional importance of PINK1 in the mitophagy cascade.
Identifier (DOI)
10.1371/journal.pbio.3002196
Tags
  • GWAS
  • Mitophagy
  • Parkin (PARK2)
  • Parkinson's disease
  • Pathomechanism
  • PINK1
  • Review
Team
Team Hardy
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

  • User avatar fallback logo

    Benjamin O’Callaghan, PhD

    Key Personnel: Team Hardy, 

    University College London

  • John Hardy, PhD

    Lead PI (Core Leadership): Team Hardy, 

    University College London

  • User avatar fallback logo

    Helene Plun-Favreau, PhD

    Collaborating PI: Team Hardy, 

    University College London

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