Key Personnel: Team Harper,
Max Planck Institute of Biochemistry
Co-PI (Core Leadership): Team Harper,
University of Gottingen
Protocol for depleting or tagging endogenous α-syn using virally-delivered CRISPR-Cas9 in hippocampal neurons
a-syn SAA positivity, DaT positivity, and hyposmia are highly associated with each other. MDS Prodromal PD Probability scores may be useful predictors of near-term progression, and thus as a stratification factor in clinical research study design
Raw data associated with DOI: 10.1038/s41467-021-22108-0
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