Key Personnel: Team Kaplitt,
Karolinska Institute
Co-PI (Core Leadership): Team Kaplitt,
Propagation of αSyn from the gut-to-the-brain induces RBD and several non-motor and motor phenotypes of Parkinson’s disease.
Protocol for freely moving pellet or water reaching, lever pressing and open field behavioral assays from Falasconi & Kanodia et al 2025.
Protocol describes dual-cue Pavlovian association & multi-fiber photometry in head-fixed mice. Mice trained to link cues with rewards & undergo extinction phase with reduced rewards.
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