By Odetta Antico, Alban Ordureau, Michael Stevens, Francois Singh, Marek Gierlinski, Erica Barini, Mollie L. Rickwood, Alan Prescott, Rachel Toth, Ian G. Ganley, J. Wade Harper and Miratul Muqit
A data-driven molecular map of the DLPFC reveals distinct spatial domains and cell populations, offering insights into neuropsychiatric disorders. The study provides a roadmap for implementing spatial clustering approaches in the human brain.
The files found here are associated to Do, Q. et al (2023) study and contain: (a) all source and supplementary data, (b) Key Resources Table, and (c) list of primers.
The results highlight the unique utility of modeling striatal neurons in a modular and highly physiological circuit, which is essential to reveal mechanistic insights of the loss of electrical functional integrity in the striata of GBA1 PD patients.
