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  • HeLa S3 RUBCN KO/HaloTag7-LC3

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    Rubicon KO S3 HeLa + HaloTag7-LC3.

  • HeLa S3 RUBCN KO/HA-Parkin/HaloTag7-mGFP

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    Rubicon KO S3 HeLa + HA-Parkin/pSu9 + HaloTag7-mGFP.

  • HeLa S3 RUBCN KO clone 15

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    Rubicon KO HeLa.

  • pmCherryC1-Rubicon

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    Mammalian expression of Rubicon.

  • pmCherryC1-Pacer

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    Mammalian expression of Pacer.

  • pmCherryC1-Pacer K534N, R623T

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    Mammalian expression of Pacer mutant.

  • Mito-SNAP

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    Encodes a mitochondrially-targeted SNAP tag for mammalian cell expression. Mitochondrial targeting signal from COX8A fused to SNAP (derived from human MGMT).

  • SNCA A30P iPSC

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    Available at Jax: SNV/WT, REV/WT, and SNV/SNV of the A30P SNCA variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000),

  • SNCA A53T iPSC

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    Available at Jax: SNV/WT, REV/WT, and SNV/SNV of the A53T SNCA variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • LRRK2 I2020T iPSC

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    Available at Jax: SNV/WT, REV/WT, and SNV/SNV of the I2020T LRRK2 variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • PINK1 A217D iPSC

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    Available at Jax: SNV/WT, SNV/SNV, and REV/REV of the A217D PINK1 variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • LRRK2 N2081D iPSC

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    Available at Jax: SNV/WT, REV/WT, and SNV/SNV of the N2081D LRRK2 variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • PRKN R42P iPSC

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    Available at Jax: SNV/WT, SNV/SNV, and REV/REV of the R42P PRKN variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • PRKN T240M iPSC

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    Available at Jax: SNV/WT, SNV/SNV, and REV/REV of the T240M PRKN variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • SNCA E46K iPSCs

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    Available at Jax: SNV/WT, Rev/WT, and SNV/SNV of the E46K SNCA variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • PRKN R275W iPSC

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    Available at Jax: SNV/WT, SNV/SNV, and REV/REV of the R275W PRKN variant. Associated with Parkinson's disease with dementia. Parental line is KOLF2.1J (JIPSC1000).

  • pMX-IG-ATG3

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    Expresses untagged ATG3 in mammalian cells.

  • pMX-IG-ATG3 (C264A)

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    Expresses untagged ATG3 (C264A) in mammalian cells.

  • pMX-IG-ATG3 (Y209A)

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    Expresses untagged ATG3 (Y209A) in mammalian cells.

  • pMX-IG-ATG3 (Y210A)

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    Expresses untagged ATG3 (Y210A) in mammalian cells.

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Aligning Science Across Parkinson's
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