Jensen_etal_2022_molecular_dynamics_simulation_data_2
By onFull molecular dynamics simulation data set accompanying Jensen et al, 2022, containing (i) representative coordinates and measurements described therein, (ii) simulation trajectories, and (iii) GROMACS input files.
Primary data associated with the manuscript 10.1073/pnas.2315171120 (“Localization of PPM1H phosphatase tunes Parkinson’s disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis”)
By onPrimary data associated with the manuscript 10.1073/pnas.2315171120 ("Localization of PPM1H phosphatase tunes Parkinson’s disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis").
Tandem Mass Tag (TMT) label-based mass spectrometry analysis of RILPL1 interactors
By onTandem Mass Tag (TMT) label-based mass spectrometry analysis of RILPL1 interactors
Mass spectrometry analysis of proteome changes in VPS35-WT vs VPS35[D620N] MEFs and VPS35[D620N] MEFs vs LRRK2 inhibitor in whole cell lysates and lysosomes
By onMass spectrometry analysis of proteome changes in VPS35-WT vs VPS35 MEFs and VPS35 MEFs vs LRRK2 inhibitor in whole cell lysates and lysosomes
Peripheral MC1R activation modulates immune responses and confers neuroprotection in a mouse model of Parkinson’s disease
By onDataset corresponding to the article, "Peripheral MC1R activation modulates immune responses and confers neuroprotection in a mouse model of Parkinson's disease."
CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X
By onProtein fibril classification for Homo sapiens, expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I
By onProtein fibril classification in Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II
By onProtein fibril from Homo sapiens expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG with no mutations reported.
CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII
By onProtein fibril classification in Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG system without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V
By onProtein fibril classification for Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type II with extended core from DLB case VII
By onProtein fibril from Homo sapiens expressed in Escherichia coli BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X
By onProtein fibril classification for Homo sapiens using Escherichia coli 'BL21-Gold(DE3)pLysS AG expression system with no mutations identified.
Alpha-synuclein fibril from spontaneous control
By onProtein fibril from Homo sapiens expressed in Escherichia coli BL21-Gold(DE3)pLysS AG without mutations.
Proteome of R1441C and G2019S LRRK2 knock in mice after striatal motor learning task
By onTo identify the signaling pathways that underlie motor learning deficits, the authors performed six-plex tandem mass tag (TMT) quantitative mass spectrometry (MS) to compare the protein expression in mice following the five days of the rotarod test.
Tabular data associated with “Synapsin E-domain is essential for α-synuclein function”
By onDataset associated with the publication "Synapsin E-domain is essential for α-synuclein function."
Data associated with “Serine-129 phosphorylation of α-synuclein is a trigger for physiologic protein-protein interactions and synaptic function”
By onDataset associated with the publication "Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function."
