Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
By onRaw data associated with DOI: 10.15252/embr.202152675
Mass spectrometry proteomic data supporting the PPM1H/Rab8A crosslinking study described in doi: 10.15252/embr.202152675
By onRaw data associated with DOI: 10.15252/embr.202152675
Primary data associated with doi: 10.1042/BCJ20220308 (PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain)
By onRaw immunoblotting data; immunofluorescence microscopy images; tabular data for quantification; autoradiograph films; scans of Coomassie-stained protein gels; Prism files with statistical analysis.
Phosphosite mapping on PI3Kc1 by ULK1 and TBK1 kinases.
By onPhosphosite mapping on PI3Kc1 by ULK1 and TBK1 kinases.
Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore: Molecular dynamics simulation data
By onAtomistic molecular dynamics simulation data set accompanying manuscript "Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore".
Jensen_etal_2022_molecular_dynamics_simulation_data_2
By onFull molecular dynamics simulation data set accompanying Jensen et al, 2022, containing (i) representative coordinates and measurements described therein, (ii) simulation trajectories, and (iii) GROMACS input files.
Primary data associated with the manuscript 10.1073/pnas.2315171120 (“Localization of PPM1H phosphatase tunes Parkinson’s disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis”)
By onPrimary data associated with the manuscript 10.1073/pnas.2315171120 ("Localization of PPM1H phosphatase tunes Parkinson’s disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis").
Tandem Mass Tag (TMT) label-based mass spectrometry analysis of RILPL1 interactors
By onTandem Mass Tag (TMT) label-based mass spectrometry analysis of RILPL1 interactors
Mass spectrometry analysis of proteome changes in VPS35-WT vs VPS35[D620N] MEFs and VPS35[D620N] MEFs vs LRRK2 inhibitor in whole cell lysates and lysosomes
By onMass spectrometry analysis of proteome changes in VPS35-WT vs VPS35 MEFs and VPS35 MEFs vs LRRK2 inhibitor in whole cell lysates and lysosomes
Peripheral MC1R activation modulates immune responses and confers neuroprotection in a mouse model of Parkinson’s disease
By onDataset corresponding to the article, "Peripheral MC1R activation modulates immune responses and confers neuroprotection in a mouse model of Parkinson's disease."
CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X
By onProtein fibril classification for Homo sapiens, expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case II
By onProtein fibril from Homo sapiens expressed in Escherichia coli strain BL21-Gold(DE3)pLysS AG with no mutations reported.
CryoEM structures of amplified alpha-synuclein fibril class B type II with extended core from DLB case I
By onProtein fibril classification in Homo sapiens expressed in Escherichia coli BL21(DE3) without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B mixed type I/II with extended core from DLB case V
By onProtein fibril classification for Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III
By onProtein fibril classification for Homo sapiens expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG without mutations.
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII
By onProtein fibril classification in Homo sapiens, expressed in Escherichia coli 'BL21-Gold(DE3)pLysS AG system without mutations.
