Aligning Science Across Parkinson's (ASAP) fosters collaboration, generates research-enabling resources, and promotes data sharing to accelerate discovery in Parkinson's disease (PD). We currently support 5 initiatives, all with the goal of advancing research for the benefit of the entire PD community. The projects listed below help fuel mechanistic research and enable biomarker studies.
The ASAP Collaborative Research Network (CRN) is an international, multidisciplinary, and multi-institutional network of collaborating investigators that facilitates the rapid and free exchange of scientific ideas to spark new discoveries for PD. Teams support productive collaborations, include diverse talents, and embrace the values of openness and transparency to accelerate outcomes and impact of findings.
The Global Parkinson’s Genetics Program (GP2) is a program aimed at ensuring ancestral diversity is included in PD-related genetic datasets to make PD genetics globally relevant through genotyping diverse patient populations and studying rare familial forms of the disease, with a commitment to global collaboration and open data, develop tools, and provide training and resources.
The Parkinson’s Progression Markers Initiative (PPMI) is a landmark observational study focused on supporting worldwide strategies for investigating and defining biomarker signatures of PD risk, onset, and progression. PPMI makes its data set and biorepository – the most robust in PD to date – available to academia and industry to accelerate breakthroughs.
The iPSC Neurodegenerative Disease Initiative (iNDI-PD) is the largest genome engineering initiative in research to date. ASAP supports iNDI-PD, an extension of the iNDI research initiative that is making induced pluripotent stem cell (iPSC) resources accessible to all researchers working on PD and drawing connections across diagnostic lines.
The Accelerating Medicine Partnership in Parkinson’s Disease (AMP® PD) is a public-private partnership to harmonize PD datasets across the community with the goal of identifying and validating diagnostic, prognostic, and/or progression biomarkers for PD, with an emphasis to broaden data sharing in the biomedical community to advance PD research.
A Catalog for Research Outputs & Tools
The ASAP Catalog showcases the research outputs and tools developed by ASAP-funded programs and researchers to foster learning and collaboration in the PD space.