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Catalog
ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.
Tool
pBPK1520-SNCA-A30P-ng
It can be used to introduce SNCA-A30P mutation using prime editing, PE3 approach.
Teams
Themes
Tool
pBPK1520-SNCA-A53T-ng
It can be used to introduce SNCA-A53T mutation using prime editing, PE3 approach.
Teams
Themes
Lab Resource
BPK1520-LRRK2-G2019S-ng
This resource can be used to introduce LRRK2-G2019S mutation using prime editing, in PE3 approach.
Teams
Themes
Lab Resource
pU6-pegRNA-LRRK2-G2019S-3d
This resource can be used to introduce LRRK2-G2019S mutation using prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-LRRK2-G2019S-3c
This resource can be used to introduce LRRK2-G2019S mutation using prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-LRRK2-G2019S-3b
This resource can be used to introduce LRRK2-G2019S mutation using prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-LRRK2-G2019S-3a
This resource can be used to introduce LRRK2-G2019S mutation using prime editing.
Teams
Themes
Lab Resource
Px330-EGFP-LRRK2-CRISPR/Cas9
This resource can be used to introduce LRRK2-G2019S mutation using CRISPR/Cas9 based genome editing.
Teams
Themes
Lab Resource
pBPK1520-HEK3-CTTins-ng
This resource can be used to introduce HEK3 CTT insertion using prime editing, PE3 approach. It serves as a good positive control for prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-SNCA-A53T
This resource can be used to introduce SNCA-A53T mutation using prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-SNCA-A30P
This resource can be used to introduce SNCA-A30P mutation using prime editing.
Teams
Themes
Lab Resource
pU6-pegRNA-HEK3-CTTins-px330-scaffold
This resource can be used to introduce HEK3 CTT insertion using prime editing. It serves as a good positive control for prime editing.
Teams
Themes
Lab Resource
pET30a(+)-PE2
This resource can be used to express and purify PE2 protein for RNP delivery.
Teams
Themes
Lab Resource
AAVS1-SA-neo-CAGGS-PE2-2A-GFP
This resource can be used to generate knock-in cell line faciliating prime editing.
Teams
Themes