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Cx3cr1-cre;Ercc1-/fl mice
onMicroglia may experience higher levels of DNA damage and potential senescence due to internal factors.
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Dan Lab sleep datasets for MCI-Park mice 24-hour recordings
onSleep-wake dataset for MCI-Park mice and wildtype controls from Dan Lab.
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pAAV-hsyn-DIO-Rpl22l1-3Flag-2A-eGFP-WPRE
onExpression of a Flag-tagged Rpl22I1 protein in cells expressing Cre recombinase allowing for the harvesting of actively transcribed mRNAs in that cell type.
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Anxa1-P2A-Cre Mouse line
onAnxa1-Cre knock-in mice express cre recombinase from the mouse Anxa1 promoter in Anxa1-expressing cells and subtypes of dopaminergic neurons. This strain is useful in studies of motor neuron deficits in Parkinson's disease.
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Slc6a3-T2A-FlpO (DAT-flpO) Mouse Line
onDAT-FlpO knock-in mice express optimized Flp recombinase (FlpO) from the mouse Slc6a3 (DAT) promoter in Slc6a3-expressing cells, including dopaminergic neurons. This strain is useful in studies of motor neuron deficits in Parkinson's disease.
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Adora2a-T2A-FlpO Mouse Line
onAdora2a-Cre line generated by Cyagen for the Costa lab crossed with a FlpO line.
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Drd1-T2A-FlpO Mouse Line
onDopamine D1 receptor FlpO mouse line generated by the Costa lab at Cyagen using CRISPR/Cas-mediated genome engineering.
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Adora2a-T2A-Cre Mouse Line
onAdora2a-Cre line generated by Cyagen using CRISPR/Cas-mediated genome engineering for the Costa lab.