Key Personnel: Team Lee,
Van Andel Institute
Curtin University
Co-PI (Core Leadership): Team Lee,
Associated with preprint: https://www.biorxiv.org/content/10.1101/2022.11.02.514817v1
This protocol details generation of ATG3 KO HeLa cells stably expressing HaloTag-LC3B.
This work reveals that OPTN mitophagy initiation is mechanistically distinct and highlights the mechanistic plasticity of selective autophagy pathways.
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